• The *effective* barrier of a reaction with (fast) pre-equilibrium

  Why the effective barrier of A ⇌ B → C is not ΔG2‡, not the height of TS2 above A, and not ΔG1‡+ΔG2‡ — the kinetics analysis behind our recent JACS paper.

  11 min read   ·   April 30, 2026

  2026   ·   kinetics   mechanism   physical-organic   ·   research-notes

• My quiet return to RSS (and why you might like it too)

  Your attention is one of the most valuable things you have; it's time for an RSS revival

  3 min read   ·   September 06, 2025

  2025   ·   RSS

• Organic chemistry is nothing but pattern recognition!?

  Organic chemistry through the lens of machine learning and human cognition

  3 min read   ·   February 01, 2024

  2024   ·   AI   learning

• Decoding “struggle” — my observations

  Regional and historical trends in using struggle as a verb

  4 min read   ·   December 01, 2023

  2023   ·   society

• Exploring thionation with Hückel molecular orbital theory

  Hückel theory reveals sulfur's electron-accepting secret

  4 min read   ·   February 01, 2023

  2023   ·   calculations